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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RECQL4
All Species:
18.18
Human Site:
Y706
Identified Species:
50
UniProt:
O94761
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94761
NP_004251.2
1208
133077
Y706
N
L
D
S
I
I
I
Y
C
N
R
R
E
D
T
Chimpanzee
Pan troglodytes
XP_520023
1208
133141
Y706
N
L
D
S
I
I
I
Y
C
N
R
R
E
D
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539222
1209
131690
V678
P
S
N
L
H
L
S
V
S
R
D
R
D
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q75NR7
1216
135105
Y728
T
L
D
S
V
I
I
Y
C
T
R
E
R
I
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9I920
1142
126164
C674
Q
E
G
C
Q
V
I
C
A
T
I
A
F
G
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920631
1380
154059
Y869
A
L
D
S
V
I
V
Y
C
T
R
R
E
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393782
1284
145763
Y821
E
C
N
S
I
I
I
Y
C
T
R
R
E
E
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001187631
1990
223246
Y1214
K
L
K
S
I
I
V
Y
C
I
R
R
E
E
T
Poplar Tree
Populus trichocarpa
XP_002315627
901
101082
C500
D
I
I
S
R
Y
L
C
D
N
N
I
S
A
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
N.A.
57.8
N.A.
65.9
N.A.
N.A.
N.A.
21.1
N.A.
41.2
N.A.
N.A.
33.2
N.A.
27
Protein Similarity:
100
99.2
N.A.
66.7
N.A.
75
N.A.
N.A.
N.A.
35.4
N.A.
56.5
N.A.
N.A.
51.3
N.A.
39.3
P-Site Identity:
100
100
N.A.
6.6
N.A.
53.3
N.A.
N.A.
N.A.
6.6
N.A.
66.6
N.A.
N.A.
60
N.A.
66.6
P-Site Similarity:
100
100
N.A.
26.6
N.A.
60
N.A.
N.A.
N.A.
13.3
N.A.
86.6
N.A.
N.A.
73.3
N.A.
80
Percent
Protein Identity:
25
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
42
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
0
12
0
0
12
0
12
0
% A
% Cys:
0
12
0
12
0
0
0
23
67
0
0
0
0
0
12
% C
% Asp:
12
0
45
0
0
0
0
0
12
0
12
0
12
23
12
% D
% Glu:
12
12
0
0
0
0
0
0
0
0
0
12
56
34
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
0
12
0
0
0
0
0
0
0
0
0
0
12
0
% G
% His:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
12
0
45
67
56
0
0
12
12
12
0
12
0
% I
% Lys:
12
0
12
0
0
0
0
0
0
0
0
0
0
0
12
% K
% Leu:
0
56
0
12
0
12
12
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% M
% Asn:
23
0
23
0
0
0
0
0
0
34
12
0
0
0
0
% N
% Pro:
12
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% P
% Gln:
12
0
0
0
12
0
0
0
0
0
0
0
0
0
12
% Q
% Arg:
0
0
0
0
12
0
0
0
0
12
67
67
12
0
0
% R
% Ser:
0
12
0
78
0
0
12
0
12
0
0
0
12
0
0
% S
% Thr:
12
0
0
0
0
0
0
0
0
45
0
0
0
0
45
% T
% Val:
0
0
0
0
23
12
23
12
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
12
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _